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Picture of The Ghrelin Receptor Gene in Animal Production

The Ghrelin Receptor Gene in Animal Production

Author(s): Yuki Fujimori, Masanori Komatsu, Yoichi Sato
Contributors: Yoichi Sato, Shimizu Kentaro, Masanori Komatsu, Yuki Fujimori, Tohru Terada;

Book Description

Ghrelin and the ghrelin receptor (GHSR1a) play a central role in growth hormone secretion, food intake, energy metabolism, and other important functions. This book summarizes the present situation of the GHSR1a gene polymorphisms and their genetic effects on growth and fatty acid component traits in domestic animals, humans and rodents. It highlights a unique molecular evolution of the GHSR1a gene among animal species, and its significant genetic and epistatic effects on carcass and fatty acid component traits in a sex-dependent fashion. The volume also shows the overdominance effect of the GHSR1a-DelR242 locus on growth and its molecular mechanisms and the central role of the bovine GHSR1a_5’UTR-(TG) repeat locus in growth and fatty acid component traits in cattle.


ISBN-13: 978-1-5275-3881-8
ISBN-10: 1-5275-3881-8
Date of Publication: 01/11/2019
Pages / Size: 195 / A5
Price: £58.99


Masanori Komatsu holds a PhD in Animal Science, and has engaged in genetic complement deficiencies in rabbits (C8α-γ/C3), and swine MHC/complement genes. He has also engaged in QTL mapping for growth traits and gene expression in endometrium in Wagyu, and in molecular biology for the ghrelin receptor gene in Wagyu. He established a laboratory (KLCBDA) in 2015, where he has continued with his studies of ghrelin receptor genes.

Yuki Fujimori holds a PhD in Veterinary Medicine, and worked for Ibaraki Prefectural Livestock Research Center, Japan, where he engaged in QTL mapping for growth traits and marbling in Wagyu. He currently works at the Nagano Animal Industry Experiment Station, Japan, researching the laboratory production of cattle embryos.

Yoichi Sato received a PhD in Animal Science in 2013, and has worked for Iwate Agricultural Research Center and Iwate Agricultural Junior College, Japan, where he engaged in teaching and training for livestock production. He is currently engaged in research at the Livestock Division of the Department of Agriculture of Iwate Prefectural Government, Japan.

Tohru Terada received a PhD in Biophysics and Biochemistry in 1999, and has served as a Project Associate Professor in the Agricultural Bioinformatics Research Unit of the Graduate School of Agricultural and Life Sciences at the University of Tokyo. He is currently an Associate Professor in the Interfaculty Initiative in Information Studies at the same institution.

Kentaro Shimizu received a PhD in Information Science in 1985, and is a Professor at the Department of Biotechnology of the University of Tokyo. His current research interests include protein structure prediction and protein interaction prediction. He is also engaged in membrane protein structure analysis and various protein function predictions using machine learning.