Meltdown and the Neuroscience of Stress

“The slimness of this volume belies its importance. Professor Eggers has built on several of his published papers and his enormous clinical experience by marshalling evidence widely, across many sub-specialities of modern medicine, across several preclinical areas, and across a large timespan of publications. In doing so, he has formulated a robust, eminently testable, model which provides a deep pathophysiological understanding of the aetiology both of a range of neuropsychiatric disorders, ranging from Alzheimer’s disease to schizophrenia, and of other all-too-common disorders such as obesity and hypertension. The Eggers Model immediately suggests attractive therapeutic options for these disorders. I cannot recommend this book too highly. The time spent reading it will be richly rewarded. It deserves a place on the bookshelves of every medical student and practising physician. Researchers, both preclinical and translational, interested in common medical diseases such as the ones mentioned above would also benefit from studying this work. The author does not assume that his readers have attended medical school. On the contrary, he takes the time patiently to walk the reader through fundamental concepts and terminology. Every so often, there are summary paragraphs which allow the reader to recap what has been covered and established in preceding pages. A smattering of well-chosen diagrams also aid the reader. Thus it is that I can confidently also recommend this book to patients, relatives and non-medical carers.”